We can trace back diabetes to ancient scripts. It finds mention in all major religious scriptures. In Hindu religion, the famous mythological idol Lord Ganesha was reported to suffer from this so called ‘disease of affluence’. His disease condition was rightly attributed to his life style. It is said that Lord Siva; father of Lord Ganesha made a magic herbal remedy which effectively treated his son

Osteoarthritis constitutes a major burden for health care besides posing great impediments to quality of life in progressively widening population of the aged.

Aim: Association of a- crystallin gene mutation with age related cataract. Methods: Detection of a- crystallin gene mutation was done in blood samples of cataract patients using PCR followed by restriction digestion. Results: In this study, we searched mutation in the exon-2 of CRYAA gene in 69 cases. The data revealed that although there was not a significant association of this gene mutation in the patients of age related cataract, but it showed that mutation in this gene increases the risk of age related cataract by about 5 times. Conclusion: Cataract is a multifactorial disorder and various etiologies including UV light exposure, diabetes mellitus and genetic predisposition have been attributed to it. Recent literature shows a strong association of various genes and cataract, especially congenital cataract and posterior polar cataract. A few studies, including those from India have shown genetic predisposition of even age related cataract.

Introduction: HIV/ AIDS pandemic has caused a resurgence of TB, resulting in increased morbidity and mortality worldwide. HIV and Mycobacterium tuberculosis have a synergistic interaction; each accentuates progression of the other. Clinical presentation of TB in early HIV infection resembles that observed in immunocompetent persons. Objective: ? To assess the socio- demographic profile and prevalence of pulmonary tuberculosis among HIV positive patients. ? To assess the clinical status in terms of their CD4 count, weight, hemoglobin percentage and WHO clinical stage. Materials and Methods: A record based study of HIV patients registered at ART center of C. R. Gardi Hospital was studied. A total of 147 patients were studied who were registered during January 2009 to December 2010 at ART center. These 147 patients’ records were separated into two groups i.e. HIV with Tuberculosis (61) and HIV without Tuberculosis (86). Data were recorded from NACO patient’s card and were analyzed.